We spent 2025 inside hundreds of clinical trials—watching what worked, what didn’t, and why. Across academic labs, emerging biotechs, and established CROs, we saw the same patterns repeat. The teams who finished on time weren’t using more sophisticated systems. They were making smarter choices about workflow, visibility, and support. Here’s what separated the teams […]

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Here’s what nobody talks about at industry conferences: many clinical research organizations now use a dozen or more different software tools to run a single trial. EDC platforms. ePRO systems. CTMS. RTSM. eConsent. Safety databases. Lab portals. Each one promising to solve a specific problem. Each one requiring its own login, training, and way of […]

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It’s 4 PM on a Friday, and you’re hunting through three different systems trying to answer one question: “Are we on track?” The data exists. The tools exist. But somehow, getting a clear answer feels like solving a puzzle with pieces from different boxes. We already have workflows, data flows, and patient flows — but […]

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Clinical trial patient recruitment is often challenging, but, in our experience, it doesn’t have to be. The data shows that ~80 percent of clinical trials are “delayed due to recruitment problems and dropout rates are high.” The overwhelming majority of trials (90 percent) have to double their original timeline to meet enrollment goals. More than […]

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Bringing Trial Activities to the Participant Lessons from the RADIAL Proof-of-Concept Trial The move toward more participant-centric clinical research has taken an important step forward. At the Clinical Pharmacology & Therapeutics journal, the first papers from the RADIAL trial, the flagship study of the Trials@Home project have now been published, offering valuable insights into how clinical research […]

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Speech Biomarkers for Alzheimer’s Disease Show Promise Across Multiple Languages The search for reliable, accessible biomarkers for early detection of cognitive decline has taken an important step forward. At AAIC 2025, our team presented data demonstrating that speech and language patterns can serve as valid digital biomarkers for Mild Cognitive Impairment (MCI) and Alzheimer’s disease […]

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Summary Clinical research shouldn’t feel like survival mode. The Flow State is about finding the balance between precision and ease — where tools work with you, not against you.  We already have workflows, data flows, and patient flows. But something different happens when everything truly connects — when your day moves smoothly, and the systems […]

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CTAD | Posters & Presentations Hilton San Diego Bayfront, 1 Park Boulevard – San Diego, CA 92101 | 1-4th December We’re excited to announce we are attending the 18th Clinical Trials on Alzheimer’s Disease (CTAD) This year’s Clinical Trials on Alzheimer’s Disease (CTAD) conference brings together global leaders advancing research and innovation in Alzheimer’s and […]

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DIS | Posters & Presentations Pfizer Innovation Research (PfIRe Lab) 1 Portland St Cambridge, MA 02139 | 5th November 09:00am – 5:30pm PST We’re excited to announce that our team will be attending the 8th Annual Digital Implementation Summit   This year’s Digital Implementation Summit brings together global leaders driving the transformation of clinical development from […]

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Closing the Gap Speech Analysis as an Objective Biomarker in MDD Trials The development of new therapies for Central Nervous System (CNS) disorders, particularly Major Depressive Disorder (MDD), is fundamentally challenged by the subjectivity and limitations of current assessment tools. Traditional measures, which often rely on patient self-reports or clinician ratings, frequently fail to capture […]

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Summary SCDM 2025 marked a turning point for clinical data management. This recap breaks down six lessons shaping the future of the field—from explainable AI to ICH-M11 and digital data flow—and offers practical steps for teams ready to modernize how they design, capture, and use clinical data. Each year, the Society for Clinical Data Management […]

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Every two years, the Center for Information and Study on Clinical Research Participation (CISCRP), an independent nonprofit organization in Boston, conducts a biennial global survey called the “Perceptions & Insights” study. The organization assesses public and patient views and experiences in clinical research. There are some early results from the 2025 CSICRP study, which are: […]

The post Patients Favor Decentralized Clinical Trials. You Can Too. appeared first on OpenClinica - Your Source for Clinical Trial Technology.

CTIS | Posters & Presentations Genentech, South San Francisco, CA, USA | 15th October 08:30am – 5:30pm PST We’re excited to announce that our team will be attending the 2nd Annual Clinical Trial Innovation Summit 2025   This years Clinical Trial Innovation Summit brings together global leaders driving the future of clinical research and we’re proud […]

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ISCTM and ECNP | Posters & Presentations Amsterdam, Netherlands | ISCTM: 9-11th October | ECNP: 11-14th October We’re excited to announce that our team will be attending the ISCTM 2025 Autumn Conference and ECNP 38th Congress 2025 This year’s program features world-class discussions on precision psychiatry, psychedelic therapies, and lessons from global clinical trials—and we’re proud to be […]

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At the risk of being blunt, some organizations execute patient recruitment for clinical trials better than others. There is much to be learned by studying and sharing the trends and insights from successful organizations. In a new playbook for patient recruitment, Executive Trends Report: Strategic Shifts Reshaping Clinical Trial Enrollment, OpenClinica shares the patient recruitment […]

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At the risk of a grievous understatement, 2025 has brought significant shifts in US federal funding priorities Clinical research, long dependent on support from the National Institutes of Health (NIH), the Food and Drug Administration (FDA) and CMS, is feeling the ripple effects. It’s still early but we are already observing that budget reallocation impacts […]

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How Picture Description Tasks Can Help Track Cognitive Health Remotely Speech as a digital biomarker in clinical research Changes in how we speak—how quickly we talk, how often we pause, and the words we choose—can be early signs of cognitive decline. People with mild cognitive impairment (MCI) or dementia due to Alzheimer’s disease (AD) often […]

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Can digital patient recruitment be both effective and ethically sound? In a word, yes. That said, there are a number of challenges that need to be managed. For example, the growing use of social and algorithmic tools in patient recruitment. A study published in 2020 found 22 percent of cancer trials used social media platforms […]

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The number of healthcare breaches is staggering. Between 2009 and 2023, healthcare institutes reported nearly 6,000 healthcare data breaches of 500+ records to the Office for Civil Rights (OCR). As a result of these breaches, more than 519 million healthcare records were exposed. The frequency of data breaches has more than doubled in recent years, […]

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Cambridge Cognition Investment, Monument Therapeutics, Announces Partnership with Foundation for the National Institutes of Health for Clinical Trial of MT1988, a Novel Treatment for Schizophrenia 19 August 2025 Cambridge UK, August 19, 2025 – Cambridge Cognition (AIM: COG), the brain health software group specialising in digital health products that advance brain health research and treatment, is […]

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